Over the past two decades, the discovery of CRISPR-Cas immune systems and the repurposing of their effector nucleases as biotechnological tools have revolutionized genome editing. The corresponding work has been captured by 90,000 authors representing 7,600 affiliations in 126 countries, who have published more than 19,000 papers spanning medicine, agriculture, and biotechnology. Here, we use tech mining and an integrated bibliometric and networks framework to investigate the CRISPR literature over three time periods. The analysis identified seminal papers, leading authors, influential journals, and rising applications and topics interconnected through collaborative networks. A core set of foundational topics gave rise to diverging avenues of research and applications, reflecting a bona fide disruptive emerging technology. This analysis illustrates how bibliometrics can identify key factors, decipher rising trends, and untangle emerging applications and technologies that dynamically shape a morphing field, and provides insights into the trajectory of genome editing
For FULL-TEXT go to https://www.liebertpub.com/doi/10.1089/crispr.2021.0001?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed
Author(s): Ying Huang, Yi Zhang, Mengjia Wu, Alan Porter, and Rodolphe Barrangou
Organization(s): Wuhan University, University of Technology Sydney, North Carolina State University
Source: The CRISPR Journal
Technological developments in nanomaterials can be tracked using patent indicators. However, the traditional International Patent Classification indicators cannot be considered conclusive, since nanotechnology is not easily defined as a field of research as well as there are different types of nanomaterials not well delineated into hierarchical codes. Therefore, text mining approaches can be used to enhance patent analysis and provide insightful trends to support research and development, competitive intelligence, and policy making. This study aims at proposing a method to classify nanomaterials into main types and mapping technological developments using an advanced text mining-based method to compile patent indicators. Patent records were provided by Derwent Innovations Index database, which indexes an enhanced bibliographic data of patents filed worldwide. A comparison between the IPC indicators and those developed here by text mining is presented. We concluded that the proposed method provides useful outcomes for decision-making, technological forecasting, and material selection process.
Author(s): Douglas Henrique Milanez, Leandro Innocentini Lopes de Faria, Daniel Rodrigo Leiva
Organization(s): Federal University of São Carlos
Source: Journal of Nanoparticle Research
In a competitive business environment, an early understanding of the dynamics of technological change is crucial to help policymakers and managers make better-informed decisions. Bibliometric analyses help in studying trends and technological evolution. Tech mining (text analyses of science and technology information resources) enhances Bibliometric analyses. However, more often than not, such analyses focus on a specific technological area, and mainly result in incremental advance forecasts. An analysis of the interconnected dynamics of technology change warrants new approaches for identifying technology emergence, technological substitution, and the influences of vital socioeconomic forces. This paper introduces a unique combination that applies a tech mining and semantic TRIZ as a case study to Dye-Sensitized Solar Cell (DSSC) technology. This methodological combination brings broader insights to the emergence of DSSC in conjunction with related technologies that affect its progress, enriching the associated technological progression’s empirical characterization.
- Techmining-semantic TRIZ helps to understand the competition influence among technologies.
- The understanding of the architectural design, the system, helps to clearly understand the role of the different components.
- Understanding the components’ role in the system helps to guide the techmining analysis and to understand the different trends.
- Using the S-AO and not the SAO problem solving, the present work is able to find other competing or not, technologies that help to understand if that will support the emergence of the original or the competing technology.
- This cross-tech-components have different role in other architectures. Perovskites, enhance silicon solar cells efficiency.
https://doi.org/10.1016/j.techfore.2021.120826 or download FULL-TEXT
Author(s):J.M. Vicente-Gomila, M.A. Artacho-Ramírez, Ma Ting, A.L.Porter
Organization(s):Universitat Politècnica de València, Beijing Institute of Technology, Search Technology
Source: Technological Forecasting and Social Change
Assessing corporate engagement with an emerging technology is essential for understanding the development of research and innovation systems. Corporate publishing is used as a system-level knowledge transfer indicator, but prior literature suggests that publishing can run counter to private sector needs for management of dissemination to ensure appropriability of research benefits. We examine the extent of corporate authorship and collaboration in nanotechnology publications from 2000 to 2019. The analysis identified 53,200 corporate nanotechnology publications. Despite the potential for limits on collaboration with corporate authors, this paper finds that eight out of 10 nanotechnology corporate publications involved authors from multiple organizations and nearly one-third from multiple countries and that these percentages were higher in recent years. The USA is the leading nation in corporate nanotechnology publishing, followed by Japan and Germany, with China ranking fourth, albeit with the greatest publication growth rate. US corporate publishing is more highly cited and less cross-nationally collaborative. Asian countries also have fewer collaborative authorship ties outside of their home countries. European countries had more corporate collaborations with authors affiliated with organizations outside of their home countries. The paper concludes that distinguishing corporate publications, while difficult due to challenges in identifying small- and medium-sized corporations and grouping variations in corporate names, can be beneficial to examining national systems of research and development
Link to FULL-TEXT https://www.researchgate.net/publication/350580880_Corporate_engagement_with_nanotechnology_through_research_publications
Author(s): Jan Youtie, Robert Ward, Philip Shapira, Alan L. Porter, Nils Newman
Organizaton(s): Georgia Institute of Technology, Search Technology
Source: Journal of Nanoparticle Research
Uncovering the driving forces, strategic landscapes, and evolutionary mechanisms of China’s research systems is attracting rising interest around the globe. One such interest is to understand the problem-solving patterns in China’s research systems now and in the future. Targeting a set of high-quality research articles published by Chinese researchers between 2009 and 2018, and indexed in the Essential Science Indicators database, we developed an intelligent bibliometrics-based methodology for identifying the problem-solving patterns from scientific documents. Specifically, science overlay maps incorporating link prediction were used to profile China’s disciplinary interactions and predict potential cross-disciplinary innovation at a macro level. We proposed a function incorporating word embedding techniques to represent subjects, actions, and objects (SAO) retrieved from combined titles and abstracts into vectors and constructed a tri-layer SAO network to visualize SAOs and their semantic relationships. Then, at a micro level, we developed network analytics for identifying problems and solutions from the SAO network, and recommending potential solutions for existing problems. Empirical insights derived from this study provide clues to understand China’s research strengths and the science policies beneath them, along with the key research problems and solutions Chinese researchers are focusing on now and might pursue in the future.
FULL-TEXT available at https://www.mitpressjournals.org/doi/pdf/10.1162/qss_a_00100
Author(s): Yi Zhang, Mengjia Wu, Zhengyin Hu, Robert Ward, Xue Zhang, Alan Porter
Organization(s): University of Technology Sydney, Chengdu Library and Information Centre (CAS), Georgia Institute of Technology
Source: Quantitative Science Studies
This article puts forth a new indicator of emerging technological topics as a tool for addressing challenges inherent in the evaluation of interdisciplinary research. We present this indicator and test its relationship with interdisciplinary and atypical research combinations. We perform this test by using metadata of scientific publications in three domains with different interdisciplinarity challenges: Nano-Enabled Drug Delivery, Synthetic Biology, and Autonomous Vehicles. Our analysis supports the connection between technological emergence and interdisciplinarity and atypicality in knowledge combinations. We further find that the contributions of interdisciplinary and atypical knowledge combinations to addressing emerging technological topics increase or stay constant over time. Implications for policymakers and contributions to the literature on interdisciplinarity and evaluation are provided.
Author(s): Seokbeom Kwon, Jan Youtie, and Alan L. Porter
Organization(s): The University of Tokyo, Georgia Institute of Technology
Source: Research Evaluation
Knowledge base construction (KBC) aims to populate knowledge bases with high-quality information from unstructured data but how to effectively conduct KBC from scientific documents with limited preknowledge is still elusive. This paper proposes a KBC framework by applying computational intelligent techniques through the integration of intelligent bibliometrics—e.g., co-occurrence analysis is used for profiling research topics/domains and identifying key players, and recommending potential collaborators based on the incorporation of a link prediction approach; an approach of scientific evolutionary pathways is exploited to trace the evolution of research topics; and a search engine incorporating with fuzzy logics, word embedding, and genetic algorithm is developed for knowledge searching and ranking. Aiming to examine and demonstrate the reliability of the proposed framework, a case of gene-related cardiovascular diseases is selected, and a knowledge base is constructed, with the validation of domain experts.
For FULL-TEXT https://doi.org/10.2991/ijcis.d.200728.001
Author(s): Yi Zhang, Mengjia Wu, Hua Lin, Steven Tipper, Mark Grosser, Guangquan Zhang, Jie Lu
Organization(s): University of Technology Sydney, 23 Strands
Source: International Journal of Computational Intelligence Systems
Patients with kidney failure can only survive with some form of kidney replacement (transplant or dialysis). Unfortunately, innovations in kidney replacement therapy lag behind many other medical fields. This study compiles expert opinions on candidate technologies for future kidney replacement therapies. A worldwide web‐based survey was conducted with 1,566 responding experts, identified via a text-mining process of scientific publications on kidney (renal) replacement therapy, indexed in the Web of Science Core Collection (period 2014‐2019). Candidate innovative approaches were categorized in line with the Kidney Health Initiative roadmap for innovative kidney replacement therapies. Most respondents expected a revolution in kidney replacement therapies: 68.59% before 2040 and 24.85% after 2040, while 6.56% expected none. Approaches anticipated as most likely were implantable artificial kidneys (38.6%) and wearable artificial kidneys (32.4%). A majority of experts expect that kidney replacement therapies can be significantly improved by innovative technologies.
Author(s): Bernardo Pereira Cabral, Joseph V. Bonventre , Fokko Wieringa , Fabio Batista Mota
Organization(s): Oswaldo Cruz Foundation, Harvard Medical School, Maastricht University
Source: Artificial Organs Year: 2020
Technological innovation is a dynamic process that spans the life cycle of an idea, from scientific research to production. Within this process, there are often a few key innovations that significantly impact a technology’s development, and the ability to identify and trace the development of these key innovations comes with a great payoff for researchers and technology managers. In this article, we present a framework for identifying the technology’s main evolutionary pathway. What is unique about this framework is that we introduce new indicators that reflect the connectivity and the modularity in the interior citation network to distinguish between the stages of a technology’s development. We also show how information about a family of patents can be used to build a comprehensive patent citation network. Finally, we apply integrated approaches of main path analysis (MPA)—namely global MPA and global key-route main analysis—for extracting technological trajectories at different technological stages. We illustrate this approach with dye-sensitized solar cells (DSSCs), a low-cost solar cell belonging to the group of thin-film solar cells, contributing to the remarkable growth in the renewable energy industry. The results show how this approach can trace the main development trajectory of a research field and distinguish key technologies to help decision makers manage the technological stages of their innovation processes more effectively.
For source 10.1109/TEM.2020.2966171
Author(s): Ying Huang, Fujin Zhu, Alan L. Porter, Yi Zhang, Donghua Zhu, Ying Guo
Organization(s): Wuhan University, Beijing Institute of Technology, University of Technology Sydney, China University of Political Science and Law
Source: IEEE Transactions on Engineering Management
This research identifies emergent topical trends of chitosan technology and its applications and constructs technological directions for business strategy in a hyper-competitive environment. A total of 2,612 scientific papers on chitosan technology published between 2010 and 2019 was retrieved from Web of Science (WoS) using various search queries. Results from ibliometric predictive intelligence (BPI) modelling highlight four major emergent topics related to technology convergence, namely shelf life, regenerative medicine, therapeutic agents, and antioxidant capacities. Four potential industries for chitosan application were identified: healthcare; cosmetics; agriculture; and food and beverages. The findings reveal a 75% increase in research publications since 2016 compared with previous years, which in turn illustrates the potential of technological goals to stimulate socially responsible research in the future.
For FULL-TEXT click HERE
Author(s): Worasak Klongthong, Nongnuj Muangsin, Chupun Gowanit, Veera Muangsin
Organization: Chulalongkorn University
Source: Proceedings: 2020 ISPIM Connects Bangkok – Partnering for an Innovative Community