Category Archives: Research Examples

Evaluation of the Development of R&D into Parkinson’s Disease through Technology Monitoring Using Patent Documents and Scientific Articles

Characterized as a progressive neurodegenerative disease caused by the loss of dopaminergic neurons in the substantia nigra, Parkinson’s disease is affecting an ever greater number of people around the world as global life expectancy rises. As the disease progresses, it has physical, mental, emotional, social, and economic impacts on the patient, eroding their quality of life. Many studies have been done to understand what leads to the onset of the disease and to develop treatments or even prevention. This study uses technology foresight by identifying patents and scientific articles related to drugs for the treatment of the disease with the purpose of assessing the progress of research over time and map out the countries and companies that control the related technologies.

Full-text available at http://www.ijrpb.org/pdf/v2-i3/4.pdf

Author(s): Karinne Marieta Carvalho , Eduardo Winter , Adelaide Maria de Souza Antunes
Organization(s): Federal University of Rio de Janeiro and National Institute of Industrial Property
Source: International Journal of Research in Pharmacy and Biosciences
Year: 2015

A bibliometric analysis of research on Central Asia during 1990–2014

A bibliometric analysis was performed in this work to evaluate the research publications on Central Asia from 1990 to 2014 based on Science Citation Index and Social Science Citation Index databases. This study presented a comprehensive overview of the field from the aspects of major journals, subject categories, outstanding keywords, leading countries, institutions and authors, as well as the research collaborations. It was identified that a total of 11,025 papers were published in 2356 journals and there had been a steady development over the past 25 years for Central Asia research. Geosciences Multidisciplinary, Geochemistry and Geophysics, Paleontology, Environmental Sciences and Zoology were the most popular subject categories. Keywords analysis indicated that “Tien Shan”, “climate change”, “taxonomy”, “new taxa”, and “health care” were the topics that generated the most interest and concern. Besides, temporal evolution of keywords revealed the rapid growth of “Central Asia Orogenic Belt” and “Zircon UPb dating”. According to research forces analysis, USA and Russian Academy of Sciences came as the leading contributors and had the dominant position in collaboration networks. This paper was a new attempt to better the understanding of the progress in Central Asia research. The findings of this study would help researchers improve the performance.

http://link.springer.com/article/10.1007/s11192-015-1727-y

Author(s): Lixian Wang, Xi Chen, Anming Bao, Xiaoyun Zhang, Miao Wu, Yun Hao, and Jingjing He
Organization: Chinese Academy of Sciences
Source: Scientometrics
Year: 2015

Innovation and Design Process Ontology

Many domain-specific ontologies exist. These ontologies are used in text mining processes to better understand text that is available within the specific domain. Example domains include specific business areas such as marketing or functional areas such as particular types of operations within the intelligence community. This paper makes a step toward developing a broad ontology for the innovation and design process as a domain. Such an ontology can be used to better understand the discussion that takes places in the design and development of new innovations and can be used to better understand the influences on that development. In many cases, the success, failure, or final direction of a new innovation may not rest upon its technical merits but on the non-technical influences during the design and development process such as political influences. This paper uses examples within the shipbuilding domain in order to take steps toward building an Innovation and Design Process Ontology that can be applied to the Technology Delivery System (TDS) framework as a means of capturing and understanding the influences on the delivery system.

http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=7273242

Author(s): C.C. Trumbach, C. McKesson, P. Ghandehari, L. DeCan, and O. Eslinger
Organization: University of New Orleans
Source:  2015 Portland International Conference on Management of Engineering and Technology (PICMET)
Year: 2015

Map of science with topic modeling: Comparison of unsupervised learning and human-assigned subject classification

The delineation of coordinates is fundamental for the cartography of science, and accurate and credible classification of scientific knowledge presents a persistent challenge in this regard. We present a map of Finnish science based on unsupervised-learning classification, and discuss the advantages and disadvantages of this approach vis-à-vis those generated by human reasoning. We conclude that from theoretical and practical perspectives there exist several challenges for human reasoning-based classification frameworks of scientific knowledge, as they typically try to fit new-to-the-world knowledge into historical models of scientific knowledge, and cannot easily be deployed for new large-scale data sets. Automated classification schemes, in contrast, generate classification models only from the available text corpus, thereby identifying credibly novel bodies of knowledge. They also lend themselves to versatile large-scale data analysis, and enable a range of Big Data possibilities. However, we also argue that it is neither possible nor fruitful to declare one or another method a superior approach in terms of realism to classify scientific knowledge, and we believe that the merits of each approach are dependent on the practical objectives of analysis.

Full-text available at http://onlinelibrary.wiley.com/doi/10.1002/asi.23596/full

Author(s): Arho Suominen and Hannes Toivanen
Organization(s): VTT Technical Research Centre of Finland and Lappeenranta University of Technology
Source: Journal of the Association for Information Science and Technology
Year: 2015

Visualization of knowledge integration in a Japanese cutting edge research institution: A multi level bibliometric perspective

The complexity of the problems facing society, such as health care, mobility, or environment, call for solutions cutting across different disciplines. This lies at the heart of interdisciplinary research. Interdisciplinarity has been strongly promoted worldwide over the recent years. For the case of Japan, a prominent example is the WPI (World Premier International Research Center) initiative. The integration of unrelated or distant bodies of knowledge – also regarded as knowledge integration, fusion, confluence, or convergence – is an essential factor for interdisciplinary research. This study aims at quantitatively and visually capturing knowledge integration in a cutting edge WPI research institution in Japan. By combining different existing approaches into one integrated framework, fuller, more holistic, insights into the knowledge integration efforts can be gained. Three levels of analysis are proposed: macro, meso, and micro; each of them targeting knowledge integration at different granularities. For each of these levels, different bibliometric based and visualization approaches are used: global research maps, science overlays, and research landscapes, respectively. The results of these analyses will not only provide key insights into the way knowledge integration efforts can be assessed in cutting edge research institutions, but also they are expected to serve as a spearheading efforts for the conduction of further `technology intelligence’ studies.

http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=7273021

Author(s): A. A. Robinson
Organization: Kyoto University
Source: 2015 Portland International Conference on Management of Engineering and Technology (PICMET)
Year: 2015

Evolution of emerging iPS cell-based therapies for age-related macular degeneration (AMD)

Stem cell-based regenerative medicine is poised to revolutionize the way diseases are treated. In recent years, induced pluripotent stem (iPS) cells, a newly stem cell species, has attracted significant attention. This paper seeks to understand the pathways along which emerging clinical research efforts in the field of iPS cells is evolved. In particular, the empirical case of age-related macular degeneration (AMD) is used, which is the world-pioneering clinical application of iPS cells. In line with the literature, this study explores the interrelations between three different pathways, such as biomedical scientific understanding, development of medical technologies, and learning in clinical practice. For this, a techmining approach is used including co-term, co-citation, and direct citation methods. Scientific publications indexed in the Thomson Reuters’ Web of Science and Elsevier’s Scopus databases form the basis of the study. This research first explores the iPS cell research landscape through the construction of a co-term map, particularly stressing the location and intensity of disease-tackling efforts; then focus on the evolution of scientific knowledge on AMD through co-citation networks and the main path algorithm on direct citations. At the researcher level, the development of four different research groups working on cell therapies for AMD is evaluated through the software CitNetExplorer. By integrating these approaches, the result shows a wider picture of the complexities inherent in the translation of knowledge into revolutionary clinical methods.

http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=7273173

Author(s): A. Avila-Robinson, N. Islam
Organization(s): Kyoto University
Source: 2015 Portland International Conference on Management of Engineering and Technology (PICMET)
Year: 2015

Strategic Intelligence on Emerging Technologies: Scientometric Overlay Mapping

This paper examines the use of scientometric overlay mapping as a tool of ’strategic intelligence’ to aid the governance of emerging technologies. We develop an integrative synthesis of different overlay mapping techniques and associated perspectives on technological emergence across the geographical, social, and cognitive spaces. To do so, we longitudinally analyse (with publication and patent data) three case-studies of emerging technologies in the medical domain. These are: RNA interference (RNAi), Human Papilloma Virus (HPV) testing technologies for cervical cancer, and Thiopurine Methyltransferase (TPMT) genetic testing. Given the flexibility (i.e. adaptability to different sources of data) and granularity (i.e. applicability across multiple levels of data aggregation) of overlay mapping techniques, we argue that these techniques can favour the integration and comparison of results from different contexts and cases, thus potentially functioning as platform for a ’distributed’ strategic intelligence for analysts and decision-makers.

Available from: http://www.researchgate.net/publication/235982047_Strategic_Intelligence_on_Emerging_Technologies_Scientometric_Overlay_Mapping

Author(s): Daniele Rotolo, Ismael Rafols, Michael M. Hopkins, Loet Leydesdorff
Organization(s): University of Sussex, Universitat Politècnica de València
Source: Journal of the Association for Information Science and Technology
Year: 2015

The evolution of the use of Foresight methods: a scientometric analysis of global FTA research output

An increasing number of quantitative and qualitative methods have been used for future-oriented technology analysis (FTA) to develop understanding of situations, enable creativity, engage experts, and provide interaction. FTA practitioners have used frequently one or a suitable mixture of these methods for their activities. Changing policy and strategy making contexts as well as enabling technologies increased the need and possibility for performing adaptive Foresight studies in order to improve decision making about the future and using making better use of limited resources. This study performs a scientometric analysis of the publications in the major FTA journals with the aim of understanding the dynamics of using Foresight methods across time. Among the other branches of FTA, including forecasting, futures, and technology assessment, a special emphasis is given on Foresight as a systematic and inclusive way of exploring long term futures, developing visions and formulating policies for action. The study aims at detecting the key Trends and Weak Signals regarding the use of existing methods and emerging ones with potential uses for Foresight activities. Further implications will be achieved with the generation of networks for quantitative and qualitative methods. This will demonstrate the most frequently combined Foresight methods by researchers and practitioners. Where possible the methods will also be cross-fertilised with the key thematic areas to illustrate the relationships between policy domains and industrial sectors covered by the scope of study with methodological choice. This output is considered to be taken as a methodological guide for any researchers, practitioners or policy makers, who might embark upon or involved in a Foresight activity. Further outputs of the study will include the identification of centres of excellence in the use of Foresight methods and collaboration networks between countries, institutions and policy domains. Overall, the paper demonstrates how scientometric tools can be used to understand the dynamics of evolution in a research field. Thus, it provides an overview of the use of methods in Foresight, and how it is distinguished from the other FTA activities; the evolutionary characteristics of methodological design and factors influencing the choice of methods; and finally a discussion on the future potentials for new cutting-edge approaches.

Author(s): Ozcan Saritas, Serhat Burmaoglu
Organization(s): Higher School of Economics (HSE)
Source:  Scientometrics http://link.springer.com/article/10.1007/s11192-015-1671-x
Year: 2015

Future of sustainable military operations under emerging energy and security considerations

Highlights
• The nature of warfare is changing thus the requirement for energy.
• Energy is a key component of sustainable operations.
• Energy trends are analyzed in three stages including generation, transfer and storage through technology mining.
• Scenarios are developed based on the future characteristics of warfare and emerging energy needs of military operations.
• Stages of military energy transformation are described and strategies for military energy are formulated.

Abstract

Due to limited energy sources and growing concerns about environment, secure, safe and sustainable energy has become one of the Grand Challenges at the global level. Likewise in many other aspects of life, energy is crucial for military forces. In parallel to the changing nature of warfare, the need for energy in military operations has increased dramatically. While energy consumption in the World War II was 1 gal per soldier per day, it was 4 gal per soldier per day during the Desert Storm operation in 1991. Not only the quantity, but also the type of energy required for military operations has changed dramatically. Shifts have been observed from individual man power to machines powered by fuel and electricity. Energy demand and type have changed further through the introduction of more sophisticated devices with new capabilities such as to enable night vision, designate targets with lasers, provide advanced sensing and communication capabilities and reduce human involvement in operations through drones and robotic technologies. Investigating the trends in changing nature of warfare and energy through review, technology mining and scientometrics, the present study develops future scenarios, and a strategic roadmap to identify priority technology areas and strategies for the future military energy R&D.

Author(s): Ozcan Saritas, Serhat Burmaoglu
Organization(s): Higher School of Economics (HSE)
Source: TF&SC
http://www.sciencedirect.com/science/article/pii/S0040162515002577
Year: 2015

Technology Early Warning Model: A New Approach Based on Patent Data

With the development of technology, more and more technical issues have been exposed, such as technical disputes, technical barriers and technical crisis. Thus, it is necessary to warn enterprises about technical deviation and predict future technology crises. Patent data can contain much information about technologies and would be useful in this setting. This paper proposes a technology early warning model based on patent data. This model helps enterprises analyse the technical crisis level and trends from four different perspectives (technical stability, technical monopoly, technical security and technical prospects).

http://ceur-ws.org/Vol-1437/ipamin2015_paper4.pdf

Author(s): Ganlu Sun, Ying Guo, Fan Yang
Organization(s): Beijing Institute of Technology
Source: Proceedings of the Second International Workshop on Patent Mining and
its Applications (IPAMIN)
Year: 2015