Category Archives: Literature Based Discovery

Nano-enabled Drug Delivery in Cancer Therapy: Literature Analysis Using the MeSH System

Background: Biomedical literature provides abundant knowledge on R&D development and emerging themes and techniques to researchers and to enhance clinical treatment. Tracing research topic activity and researcher connections, and understanding evolving research landscapes, support identification of research domain potential and … Continue reading

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Nano-enabled drug delivery systems for brain cancer and Alzheimer’s disease: research patterns and opportunities

“Tech mining” applies bibliometric and text analytic methods to scientific literature of a target field. In this study, we compare the evolution of nano-enabled drug delivery (NEDD) systems for two different applications – viz., brain cancer (BC) and Alzheimer’s disease … Continue reading

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Literature-related discovery and innovation: Chronic kidney disease

Different approaches for preventing, reducing, halting, and reversing chronic kidney disease (CKD) have been described in the medical literature. However, all related factors have not been identified together. To overcome these limitations, we used an LRDI-based methodology (potentially applicable to … Continue reading

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Combined biological and health effects of electromagnetic fields and other agents in the published literature

Electromagnetic field (EMF) radiation exerts both stand-alone and combined effects on biological systems. The present study examines the scope of the combined effects; i.e., identify effects on biological systems from combined exposure to electromagnetic fields/radiation and at least one other … Continue reading

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A knowledge discovery method based on analysis of multiple co-occurrence relationships in collections of journal papers

This paper explores a method of knowledge discovery by visualizing and analyzing co-occurrence relations among three or more entities in collections of journal articles.

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Literature-related discovery (LRD): Potential treatments for Multiple Sclerosis

Literature-related discovery (LRD) is the linking of two or more literature concepts that have heretofore not been linked (i.e., disjoint), in order to produce novel, interesting, plausible, and intelligible knowledge (i.e., potential discovery). The open discovery systems (ODS) component of … Continue reading

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